Endocrine Abstracts

Introduction: Severe haemorrhage from an adenoma is rare and potentially fatal. We report an unusual case of idiopathic unilateral severe adrenal haemorrhage from a non-functioning adrenal adenoma which was incidentally discovered 12 years earlier.Case Presentation: A 59-year-old female was admitted to the hospital for a severe sudden onset of abdominal pain associated with vomiting. About 12 years ago, she was found incidentally to have a left adrenal a...

Introduction: Although the first-line treatment of insulinoma remains to be surgical resection, medical therapy is necessary for non-localizable or non-resectable tumors, poor surgical candidates, or when surgery is declined. We present an interesting case of a patient with well-controlled insulinoma on diazoxide for 5 years who presented acutely with diabetic ketoacidosis (DKA).Case presentation: A 85-year-old female presented to the Emergency Departmen...

Introduction: Management of severe hyponatremia is challenging because of the need to balance the risk of overcorrection leading to osmotic demyelination syndrome (ODS) as well as under-correction causing complications, particularly in a patient with hypocortisolism and hypothyroidism. Case reports of patients with Noonan syndrome with hypopituitarism are rarely reported in literature. We report a case of a patient with Noonan syndrome and untreated anterior hypopituitarism wh...

Introduction: Obesity is a major risk factor for mortality from a range of causes. We investigated whether skinfold measurements predict mortality independently of variation in body mass index (BMI).Methods: A prospective analysis of mortality in 870 apparently healthy adult Caucasian men participating in an occupational health cohort was undertaken. At baseline, skinfold measurements were taken at biceps, triceps, iliac and ...

Introduction: Obesity is a major risk factor for mortality from a range of causes. We investigated whether skinfold measurements predict mortality independently of variation in body mass index (BMI).Methods: A prospective analysis of mortality in 870 apparently healthy adult Caucasian men participating in an occupational health cohort was undertaken. At baseline, skinfold measurements were taken at biceps, triceps, iliac and ...

Background: Lipoprotein(a) (Lp(a)) is an independent, causal, genetic risk factor for cardiovascular disease (CVD). Coronary artery calcium (CAC), measured by computerised tomography (CT) scans, is a known marker for atherosclerosis. CT Agatston scores, also known as CAC scores, are thought to be better predictors of CVD than traditional risk factors. There is conflicting data regarding the relationship between Lp(a) levels and CAC. A preliminary study has suggested a positive...

Background: Increased adiposity is associated with increased cardiovascular disease (CVD) risk but among overweight individuals clarification is needed of relationships between insulin sensitivity, fat distribution and metabolic health that might contribute to this risk.Methods: During the Heart Disease and Diabetes Research Indicators in a Screened Cohort (HDDRISC) study, 560 employment cohort normoglycaemic (FPG less than 7...

Background: Increased adiposity is associated with increased cardiovascular disease (CVD) risk but among overweight individuals clarification is needed of relationships between insulin sensitivity, fat distribution and metabolic health that might contribute to this risk.Methods: During the Heart Disease and Diabetes Research Indicators in a Screened Cohort (HDDRISC) study, 560 employment cohort normoglycaemic (FPG less than 7...